Zopiclone Side Effects

Understanding What to Expect Before starting

Introduction

Zopiclone is normally used as a short-term solution to treat insomnia, especially when the problem is starting to affect daily life. Zopiclone helps you fall asleep faster and sleep longer by slowing down the activity in the brain.

But, as with all medications, zopiclone can have side effects. 

Not everybody gets them, and they are usually minor and temporary. Nevertheless, being aware of the zopiclone side effects that you might feel will enable you to take the drug more confidently and effectively.

In the UK, zopiclone is only prescribed after medical assessment, and its use is always under medical guidance.

Reviewed by a Healthcare Professional

This content has been reviewed by a qualified healthcare professional for accuracy and consistency with current UK guidelines on the management of sleep and insomnia.

Why trust this information?

✔ Based on UK clinical guidelines

✔ Evidence-informed sleep treatment approaches

✔ Prescribed where appropriate, after assessment

Common Side Effects of Zopiclone

The common side effects of zopiclone are mild and tend to occur early on in treatment.

The most common side effect is the bitter or metallic aftertaste, which is usually noticed when waking. Although unpleasant, this side effect is harmless and will disappear over time.

Other common side effects of zopiclone are:

  • Dry mouth
  • Drowsiness the next day
  • Headaches
  • Light-headedness

Zopiclone side effects UK patients experience are usually temporary. As the body gets used to the drug, the side effects tend to diminish.

  • Drowsiness the next day is also possible, especially if the sleep is less than expected or if the drug is taken later than expected. With an adequate sleep period, this side effect can be minimized.

Overall zopiclone side effects are mostly manageable and do not need stopping treatment.

Less Common Side Effects

There are some people who may experience unusual zopiclone side effects.

These side effects can include:

  • Nausea
  • Decreased alertness
  • Confusion
  • Mood changes such as irritability
  • Blurred vision
  • In some cases, a person may experience difficulty concentrating or a feeling of slowed thinking.

These are more likely to occur when the treatment is started or when the dosage is higher. While they can cause some distress, they are generally temporary and disappear as the body gets used to the treatment.

If the symptoms are prolonged and are affecting the ability to get on with life, it is a good idea to get advice from a professional. 

Monitoring the way the body reacts can help zopiclone risks and side effects to be managed effectively.

Serious Side Effects (Rare)

Severe side effects of zopiclone are rare, and immediate action is required if any of these are experienced:

Allergic reactions such as swelling of the face, lips, or throat

  • Difficulty in breathing
  • Severe confusion or unusual behaviour
  • Memory problems, such as amnesia
  • Hallucinations

In rare cases, people may get up and walk or even eat while still not fully awake, without any memory of the events.

These are considered to be significant zopiclone risks, even though these are experienced rarely.

If any of these are experienced, immediate medical help is required.

Being aware of these rare side effects ensures that the medication is used responsibly.

Next-Day Effects (“Hangover Effect”)

Some people may have the following effects the next day after taking zopiclone like:

  • Sleepiness
  • Slower reaction times
  • Difficulty concentrating

This is called the ‘hangover effect’ and is more likely if:

  • The drug is taken late at night
  • Not enough sleep is obtained
  • A larger dose than necessary is taken

Care should be taken not to drive if the ‘hangover effect’ is experienced.

Risk of Dependence and Withdrawal

One of the more significant factors to consider is the risk of long-term side effects zopiclone may cause, such as dependence.

With prolonged use:

  • The body may be dependent on it for sleep
  • Sleep problems may return if it is stopped abruptly

Possible withdrawal symptoms:

  • Anxiety
  • Restlessness
  • Insomnia rebound

For this reason, zopiclone is only recommended for short-term use. If it is to be discontinued, it can be gradually reduced under medical supervision.

Who Is More Likely to Experience Side Effects?

Some people are more likely to have side effects from zopiclone. UK doctors are careful to monitor these types of people.

These people include:

  • Older people
  • People with liver or kidney disease
  • People taking other medicines that affect the central nervous system.

In these cases, the dose is often reduced to minimize risk

How to Reduce the Risk of Side Effects

The risk of side effects of zopiclone can be minimized if:

  • The medication is taken strictly as prescribed
  • Alcohol is avoided
  • The medication is used for the prescribed time only
  • The medication is taken just before going to bed

By doing this, the safety and efficacy of the medication are improved.

When to Consult a Doctor

You need to consult a doctor if:

  • The side effects are severe or persist or worsen
  • You are feeling excessively sleepy during the day
  • You are feeling confused, have difficulty remembering things, or behave abnormally

Early help can prevent complications and ensure proper care.

Alternatives to Zopiclone

Non-pharmacological therapies such as cognitive behavioral therapy for insomnia, sleep hygiene, and lifestyle modifications are often recommended.

Learn more about treatment options

Summary

Generally, zopiclone side effects are mild, temporary, and controllable. Common side effects include a metallic taste, dry mouth, and mild drowsiness.

While serious side effects are rare, they do exist and should be recognized. Always take medical professionals help if you feel the side effects are not controllable.

Zopiclone, when used properly and for a short time, can be a valuable sleep aid.

References

  • NHS
  • British National Formulary (BNF)
  • NICE

FAQs

What are the common side effects of zopiclone?

The common side effects of zopiclone include metallic taste, dry mouth, and next-day drowsiness.

Are zopiclone side effects UK patients experience serious?

Most zopiclone side effects UK patients report are mild, but serious effects are rare.

How long do side effects of zopiclone last?

Most side effects of zopiclone improve within a few days.

Can long term use cause issues?

Yes, long term side effects zopiclone may include dependence and withdrawal symptoms.

Is zopiclone safe to use?

Is zopiclone safe depends on correct use under medical supervision.

What are the main zopiclone risks?

Key zopiclone risks include drowsiness, dependence, and rare behavioural effects.